| 1. | Functional genomics uses as its starting point the isolated gene whose function is to be determined , and then selects a model organism in which a homolog of that gene exists 功能基因组用功能不明的分离基因作为起始点,然后选择具有该同源基因的生物模型。
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| 2. | We report here the cloning of a homolog of this gene from dunaliella salina . this cloned gene produces as protein with photolyase activity when expressd in escherichia coli 运用blast方法对est序列进行分析,初步预测该est序列为光裂合酶蓝光受体蛋白质家族中一个成员的部分cdna 。
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| 3. | Moreover the pf40 gene was ubiquity distributed in cereal crop genome . dicots such as tobacco and tomato do not have the pf40 homolog gene , but we found its homolog gene maybe present in arabidopsis genome 用该基因与玉米、小麦、水稻主要禾本科作物的基因组dna杂交,结果表明pf40基因及其同源基因普遍存在于禾谷类植物中,同时在拟南芥基因组中也有pf40基因的同源序列。
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| 4. | Dreb - type transcription factors can accept stress signals from environment and promote the expression of stress - tolerant genes . four dreb homolog genes , gmdreba , gmdrebb , gmdrebc and osdreb4 - 2 were isolated from soybean [ glycine max ( l . ) merr . ] Dreb类转录因子能接受逆境信号并启动逆境应答基因的表达。在本研究中,以大豆和水稻为材料,共克隆了4个dreb的同源基因,分别命名为gmdreba , gmdrebb , gmdrebc和osdreb4 - 2 。
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| 5. | A homolog of ga sbeta - hydroxylase gene expression pattern was examined . hybridization signals of this gene could be detected at day 5 and however , they appear again after day 10 when explants cultured with hormones . it has the similar pattern when the explants cultured without hormones or uncultured 风信子ga羟基化酶类似基回在外植体表达,在含有外源撒素条件下培养的前5天受到激素的抑制而几乎不表达,第10天开始在花分生组织中表达。
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| 6. | Notch interaction with its ligands induces the cleavage of its intracellular domain ( ic ) , and the notch ic translocates to the nucleus and binds to rbp - j , the mammalian homolog of su ( h ) , to transactivate transcription of target genes such as e ( spl ) ( enhancer of split ) , hesl ( hairy and enhancer of split ) and hes5 four notch receptors and their ligands are differentially and redundantly expressed in a variety of vertebrate tissues 它通过其识别序列( cogtgggaa )结合于受调控基因的启动子区,在转录激活因子的驱动下调节细胞分化和个体发育相关基因的表达。在没有n 。 tch胞内段的情况下, rbpj可与包含sm盯( silencingmediatorforretlnoldandthyroidhormonereceptor )和组蛋白去乙酞化酶的转录辅助抑制复合物结合,当notch信号被激活时; rbpj可与n 。
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| 7. | The two single - pass transmembrane proteins , delta and serrate , have been identified as notch ligands . the transcription factor suppressor of hairless [ su ( h ) ] is the major downstream effector of notch signaling pathway . rbp - j , the mammalian homolog of su ( h ) , recognizes the core sequence ( c / tgtgggaa ) of dna Rbp - j是果蝇促神经发生基因su ( h ) ( suppressorofhairless )在哺乳动物的同源物,它通过其识别序列( c tgtgggaa )结合于受调控基因的启动子区,在转录激活因子的驱动下调节细胞分化和个体发育相关基因的表达。
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| 8. | The tumor cells transfected with restin are arrested in gl phase and the cell proliferation is inhibited . it implies that restin may be correlated to cell cycle regulation . other data showed that the necdin , a homolog of restin , could suppress cell growth by interacting with transcription factor e2f1 and p53 而与restin的同源蛋白的necdin ,可以与细胞周期促进蛋白sv40大t抗原、腺病毒eia 、转录因子ezfi等相互作用,抑制细胞生长;也可以和转录因子p53作用参与生长抑制和抑制p53诱导的细胞凋亡。
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| 9. | Many studies show that leafy is high homolog even among distantly related plant species . exception of these , little studies on tissue culture and transformation of ginkgo have been done . this paper emphasizes on the isolation , cloning and analysing two ginkgo orthologs of leafy from the male tree 为此,本实验从银杏leafy同源基因的克隆入手,分析其雌雄株lfy基因结构差异,构建lfy基因的植物正义反义表达载体,建立矮牵牛遗传转化体系,以研究银杏lfy同源基因的功能,同时建立了银杏组织培养体系,为银杏的遗传转化和提早开花结果奠定基础。
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